diff --git a/qutebrowser/browser/browsertab.py b/qutebrowser/browser/browsertab.py
index 087834e53..9c27e470e 100644
--- a/qutebrowser/browser/browsertab.py
+++ b/qutebrowser/browser/browsertab.py
@@ -666,9 +666,10 @@ class AbstractAudio(QObject):
     muted_changed = pyqtSignal(bool)
     recently_audible_changed = pyqtSignal(bool)
 
-    def __init__(self, parent=None):
+    def __init__(self, tab, parent=None):
         super().__init__(parent)
         self._widget = None
+        self._tab = tab
 
     def set_muted(self, muted: bool):
         """Set this tab as muted or not."""
diff --git a/qutebrowser/browser/webengine/webenginetab.py b/qutebrowser/browser/webengine/webenginetab.py
index cfb809097..5a3042ba9 100644
--- a/qutebrowser/browser/webengine/webenginetab.py
+++ b/qutebrowser/browser/webengine/webenginetab.py
@@ -638,6 +638,7 @@ class WebEngineAudio(browsertab.AbstractAudio):
         page = self._widget.page()
         page.audioMutedChanged.connect(self.muted_changed)
         page.recentlyAudibleChanged.connect(self.recently_audible_changed)
+        self._tab.url_changed.connect(self._on_url_changed)
 
     def set_muted(self, muted: bool):
         page = self._widget.page()
@@ -651,6 +652,11 @@ class WebEngineAudio(browsertab.AbstractAudio):
         page = self._widget.page()
         return page.recentlyAudible()
 
+    def _on_url_changed(self):
+        urlstr = self._tab.url().toString(QUrl.RemoveUserInfo)
+        muted_url = config.instance.get('content.mute', url=urlstr)
+        self.set_muted(muted_url is not None)
+
 
 class _WebEnginePermissions(QObject):
 
@@ -995,7 +1001,7 @@ class WebEngineTab(browsertab.AbstractTab):
         self.printing = WebEnginePrinting(tab=self)
         self.elements = WebEngineElements(tab=self)
         self.action = WebEngineAction(tab=self)
-        self.audio = WebEngineAudio(parent=self)
+        self.audio = WebEngineAudio(tab=self, parent=self)
         self._permissions = _WebEnginePermissions(tab=self, parent=self)
         self._scripts = _WebEngineScripts(tab=self, parent=self)
         # We're assigning settings in _set_widget
diff --git a/qutebrowser/browser/webkit/webkittab.py b/qutebrowser/browser/webkit/webkittab.py
index 7b7ad0c7d..28d27f919 100644
--- a/qutebrowser/browser/webkit/webkittab.py
+++ b/qutebrowser/browser/webkit/webkittab.py
@@ -661,7 +661,7 @@ class WebKitTab(browsertab.AbstractTab):
         self.printing = WebKitPrinting(tab=self)
         self.elements = WebKitElements(tab=self)
         self.action = WebKitAction(tab=self)
-        self.audio = WebKitAudio(parent=self)
+        self.audio = WebKitAudio(tab=self, parent=self)
         # We're assigning settings in _set_widget
         self.settings = webkitsettings.WebKitSettings(settings=None)
         self._set_widget(widget)
diff --git a/qutebrowser/config/configdata.yml b/qutebrowser/config/configdata.yml
index 7d39bded8..bde38cbb8 100644
--- a/qutebrowser/config/configdata.yml
+++ b/qutebrowser/config/configdata.yml
@@ -746,6 +746,14 @@ content.xss_auditing:
     Suspicious scripts will be blocked and reported in the inspector's
     JavaScript console.
 
+content.mute:
+  default: null
+  type:
+    name: String
+    none_ok: true
+  supports_pattern: true
+  desc: List of URLs muted by default.
+
 # emacs: '
 
 ## completion